As an example, here are images of Anastasia, a lead character from J.S. Frankel's novel "Catnip".
Harry Goldman, teenage DNA researcher, genius, and total nerd, is thrown into jail for illegal transgenic research. Freed by the FBI on the condition he works under their aegis, Harry is taken to New York where he meets Anastasia, a cat-girl and the product of transgenic engineering. No sooner do they get acquainted then they are attacked by another creature, a bear which is more than a bear, and are forced to flee for their lives. Along the way, they encounter furries, Doug the Dog, find out that they are more into each other emotionally than they’re willing to admit, and end up in the Catskill Mountains where Harry finds out the shocking truth about how Anastasia was created...and what she was created for.
The cover above shows Anastasia from "Catnip".
Here is her character in anime.